When it comes to memory as a general rule of thumb is to have as much as you can. Of course if you can get fast memory that is just a bonus.
Legit reviews has posted a small article on the effects of memory size and gaming under 64-bit Windows Vista, check it out.
Game Testing 2GB versus 4GB of Memory on Vista 64-bit@ Legit Reviews
Oh and don't forgetMemory LOVES company.
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